Saccharomyces cerevisiae aids liver healthEngineered S. cerevisiae-pYD1-ScFv-AFB1 mitigates aflatoxin B1 toxicity via bio-binding and intestinal microenvironment repair.
We explored the potential of an engineered yeast, S. cerevisiae-pYD1-ScFv-AFB1, in addressing liver damage caused by aflatoxin B1 (AFB1), a known cancer risk factor. Using a mouse model, we treated subjects with this specialized yeast for four weeks.
The results showed that the engineered yeast significantly reduced inflammation and cellular damage in the liver, and improved antioxidant capacity. Additionally, it helped repair the intestinal barrier disrupted by AFB1. These findings suggest it may offer a new way to combat AFB1 toxicity.
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Saccharomyces-driven protection against liver toxicityThe mechanistic interplay between Nrf-2, NF-κB/MAPK, caspase-dependent apoptosis, and autophagy in the hepatoprotective effects of Sophorolipids produced by microbial conversion of banana peels using Saccharomyces cerevisiae against doxorubicin-induced hepatotoxicity in rats.
We explored how sophorolipids, produced by Saccharomyces cerevisiae using banana peels, could guard against liver damage caused by the chemotherapy drug doxorubicin (DOX). In our study with male Wistar rats, we compared the effects of sophorolipid treatment against DOX alone.
The results showed that applying sophorolipids improved liver function and adjusted key markers related to oxidative stress and inflammation. In essence, the sophorolipids appeared to offer protection against the harmful effects of DOX on the liver.
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Yeast boosts seabream health against cadmiumSaccharomyces cerevisiae supplemented diets mitigate the effects of waterborne cadmium toxicity on gilthead seabream (Sparus aurata L.): growth performance, haemato-biochemical, stress biomarkers, and histopathological investigations.
We investigated whether adding Saccharomyces cerevisiae, a type of yeast, to the diet of gilthead seabream could lessen the harmful effects of waterborne cadmium. In a controlled setting, fish were split into groups that received different amounts of yeast and varying levels of cadmium exposure over two months.
Our results showed that higher yeast levels improved growth and reduced stress-related health indicators in fish affected by cadmium, while lower levels did not offer significant protection. Although cadmium levels increased in the fish exposed to it, those fed with yeast diets exhibited less contamination and better health overall.
This study suggests that incorporating 1.0% yeast into seabream diets can enhance welfare and mitigate cadmium's negative effects.
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Saccharomyces improves cow healthEffect of supplementing live Saccharomyces cerevisiae yeast on performance, rumen function, and metabolism during the transition period in Holstein dairy cows.
We looked into how adding live Saccharomyces cerevisiae yeast affects dairy cows during their transition period. Our study compared ten Holstein cows given either yeast supplementation or a regular diet. We found that those with yeast had better food intake, increased rumination time, and potentially higher milk production.
The yeast also seemed to help reduce inflammation and improve liver health, shown by lower blood inflammation markers. Overall, Saccharomyces cerevisiae supplementation positively impacts rumen function and could lower metabolic disease risk, making it a helpful addition for dairy farmers.
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